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GHRP–6 is a secretagogue peptide that is considered to be a hexipeptide. What this means is, it is a peptide chain whose structure consists of six amino acids. Its molecular formula is C46H56N12O6, and it carries a molecular weight of 873.014.

GHRP–6 and the Pituitary Gland

According to scientific study based on animal test subjects, GHRP 6’s functionality is primarily tied to the pituitary gland. This is the pea-sized gland that is located at the bottom of the hypothalamus at the base of the brain and is responsible for the control and regulation of several key bodily functions, ranging from growth and blood pressure to water regulation and pain relief. GHRP 6’s presence causes the natural inhibition of the gland’s secretion properties to cease, meaning that it allows the gland to boost its expression of the secretions relating to these important endocrine-related functions.

GHRP–6 and Ghrelin

GHRP 6’s ability to boost the functionality of the pituitary gland’s secretions is also tied to the peptide’s capacity to stimulate ghrelin; an amino acid that is primarily produced by the stomach of animal test subjects as a means to stimulate hunger. The peptide enables an elevated level of ghrelin to be produced, which in turn allows for an elevated desire for an animal test subject to consume food. The extra intake of food is then converted into the boosted energy that is needed in order for the pituitary gland to produce its elevated levels of secretion.

GHRP – 6 and the Central Nervous System

Another aspect of GHRP – 6 and its overall functionality is tied to the central nervous system of an animal test subject. Studies have determined that the peptide enables an elevated secretion level of IGF – 1. This expression, whose molecular structure is similar to insulin, is thought to be the primary active agent for the secretion that causes growth. This increased expression has been determined to travel through the animal test subject’s body via the central nervous system. Additionally, it has been determined that this increased expression through the central nervous system causes a greater level of protein expression in neuroprotection, also known as cell survival.

GHRP – 6 and Bodily Regulation

Because of GHRP – 6’s relationship with the pituitary gland and ghrelin, scientific study based on animal test subjects have determined that the peptide contains the ability to elevate a host of processes relating to bodily regulation. Some of these regulatory processes include:

  • An increase in muscle growth
  • An increase in bone tissue growth
  • An elevated immune system efficiency
  • An increased strength in joints an connective tissue

Further studies on GHRP -6’s associations with the pituitary glands and ghrelin have led to the conclusion that the peptide can cause a decrease in the level of body fat amongst animal test subjects. The reasoning behind this theory ties to the peptide’s ability to elevate the pituitary gland’s levels of secretion. These boosted secretion levels are in part fueled by an animal test subject’s increased intake of food; a desire that is stimulated by GHRP-6’s ability to promote the production of ghrelin. One of these increased processes that are tied to the pituitary gland’s elevated expression is the process of lipolysis, that is, the breaking down of fat. That said, this process can be counteracted by sedentary means; scientific studies on animal test subjects have determined that if the increase in food is not converted into energy, the level of fat on an animal test subject can increase.

GHRP – 6 and Ischemic Injury

Other scientific study based on animal test subjects have determined that GHRP – 6’s capacity to facilitate cell survival via the activation of intracellular signaling pathways can theoretically aid the recovery process in the wake of an ischemic injury; that is, an injury that is marked by a shortage of oxygen and glucose to cells due to a restriction in blood supply to tissues. It is thought that the peptide’s ability can effectively safeguard cellular loss and function during an ischemic episode by easing the process in which the elevated secretions brought upon by the peptide’s functionality can be delivered.

For Scientific Research Only

Although there has been an extensive amount of research and study conducted in relation to GHRP – 6 and its overall functionality, operational mechanics, and theorized benefits, it should be noted that all of the research that has been conducted and the subsequent results from such research has been solely built around the scientific study based on animal test subjects. The peptide is solely intended for the use of scientific study at this point in time. As such, any findings or observations that relate to GHRP –6’s overall functionality, mechanics, or theoretical benefits, should only be contained to the strict confines of a controlled environment such as a medical research facility or a laboratory.